Gene description for Pdcd6ip |
Gene name |
programmed cell death 6 interacting protein |
Gene symbol |
Pdcd6ip |
Other names/aliases |
Aip1 Alix Eig2 mKIAA1375 |
Species |
Mus musculus |
Experiment description of studies that identified Pdcd6ip in Melanoma cells |
1
|
Experiment ID | 1167 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29907695
|
Organism | Mus musculus |
Experiment description | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. |
Authors | Steenbeek SC, Pham TV, de Ligt J, Zomer A, Knol JC, Piersma SR, Schelfhorst T, Huisjes R, Schiffelers RM, Cuppen E, Jimenez CR, van Rheenen J. |
Journal name |
EMBO J.
|
Publication year | 2018 |
Sample | Melanoma cells |
Sample name | B16F1 (16.5 K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry RNA sequencing |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 1168 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29907695
|
Organism | Mus musculus |
Experiment description | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. |
Authors | Steenbeek SC, Pham TV, de Ligt J, Zomer A, Knol JC, Piersma SR, Schelfhorst T, Huisjes R, Schiffelers RM, Cuppen E, Jimenez CR, van Rheenen J. |
Journal name |
EMBO J.
|
Publication year | 2018 |
Sample | Melanoma cells |
Sample name | B16F10 (16.5 K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry RNA sequencing |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 1169 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29907695
|
Organism | Mus musculus |
Experiment description | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. |
Authors | Steenbeek SC, Pham TV, de Ligt J, Zomer A, Knol JC, Piersma SR, Schelfhorst T, Huisjes R, Schiffelers RM, Cuppen E, Jimenez CR, van Rheenen J. |
Journal name |
EMBO J.
|
Publication year | 2018 |
Sample | Melanoma cells |
Sample name | B16F1 (100 K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry RNA sequencing |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 1170 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29907695
|
Organism | Mus musculus |
Experiment description | Cancer cells copy migratory behavior and exchange signaling networks via extracellular vesicles. |
Authors | Steenbeek SC, Pham TV, de Ligt J, Zomer A, Knol JC, Piersma SR, Schelfhorst T, Huisjes R, Schiffelers RM, Cuppen E, Jimenez CR, van Rheenen J. |
Journal name |
EMBO J.
|
Publication year | 2018 |
Sample | Melanoma cells |
Sample name | B16F10 (100 K) |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry RNA sequencing |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 2981 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Mus musculus |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Melanoma cells |
Sample name | B16-F10 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 2982 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
MISEV | Large EVs |
Identification method | Western blotting
|
PubMed ID |
30089911
|
Organism | Mus musculus |
Experiment description | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response |
Authors | Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. |
Journal name |
Nature
|
Publication year | 2018 |
Sample | Melanoma cells |
Sample name | B16-F10 - 16.5k pellet |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 3205 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
34957415
|
Organism | Mus musculus |
Experiment description | Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors | García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year | 2021 |
Sample | Melanoma cells |
Sample name | B16-F1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 3206 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
34957415
|
Organism | Mus musculus |
Experiment description | Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors | García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year | 2021 |
Sample | Melanoma cells |
Sample name | B16-F10 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 3207 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
34957415
|
Organism | Mus musculus |
Experiment description | Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors | García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year | 2021 |
Sample | Melanoma cells |
Sample name | B16-F1R2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting Mass spectrometry Flow cytometry |
EV-TRACK |
-
|
|
|
10
|
Experiment ID | 3208 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
34957415
|
Organism | Mus musculus |
Experiment description | Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors | García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year | 2021 |
Sample | Melanoma cells |
Sample name | B16-F10 - Fraction 6 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 3209 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
34957415
|
Organism | Mus musculus |
Experiment description | Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors | García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year | 2021 |
Sample | Melanoma cells |
Sample name | B16-F1R2 - Fraction 5 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 3210 |
Identified molecule | protein
|
Extracellular vesicle type | Small extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
34957415
|
Organism | Mus musculus |
Experiment description | Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism |
Authors | García-Silva S, Benito-Martín A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÁ, Torres-Ruiz R, Rodríguez-Perales S, Martínez L, Pérez-Martínez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, Martínez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, Megías D, Mehrara BJ, Lyden D, Peinado H. |
Journal name |
Nat Cancer
|
Publication year | 2021 |
Sample | Melanoma cells |
Sample name | B16-F1R2 - Fraction 6 |
Isolation/purification methods | Differential centrifugation OptiPrep density gradient centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|